The series is set in the 21st century where the existence of humanoid animals known as beastmen, who have been living in the darkness for centuries, has been revealed to the world. One day, Michiru, who was a normal high school student, suddenly turns into a tanuki beastman; running away, she seeks refuge in Anima City, a place set up for beastmen to be able to live as themselves. While there, Michiru encounters a wolf beastman, Shirou Ogami, who goes on to investigate why she became a beastman, and in the process gets mixed up in even stranger events